Discovering and developing innovative therapeutics for CNS disorders

Welcome to the Newron Pharmaceuticals website.
We are a clinical-stage biopharmaceutical company. Our shares are listed on the SIX Swiss Exchange (NWRN). Our mission is to discover, develop and commercialise novel drugs to treat diseases of the Central Nervous System (CNS) and pain.

Research & Drug Development

2010

Cognitive impairment and anticholinergic therapy in patients with Parkinson's diseases

R Anand,V Lucini, E Forrest, R Giuliani, S De Santi, R Chugh, P Rice, for the Study 016 Investigators

7th International Congress on Mental Dysfunction and Other Non-Motor Features in Parkinson' s Disease (MDPD) - Barcelona, Spain, 9-12 December 2010

 

The dual dopaminergic and non-dopaminergic actions of safinamide improve motor and depressive symptoms in patients with mid-late stage Parkinson ' s disease

V Lucini, R Borgohain, N A. Mehta, O Bajenaru, R Quatrale, R Anand, for the Study 016 Investigators

7th International Congress on Mental Dysfunction and Other Non-Motor Features in Parkinson' s Disease (MDPD) - Barcelona, Spain, 9-12 December 2010

 

Adjuvant activity of the novel sodium channel blocker NW-3509 in combination therapy with antipsychotics                                                       

E. Izzo, A. Ieraci, S. Meli, P. Salvati, M. Bortolato, R. Frau, V. Bini, R. Anand

Neuroscience 2010 -  40th annual meeting, Nov. 13-17 San Diego, CA                                          

 

Effects of safinamide as add-on to L-dopa on motor and depressivesymptoms in patients with mid- to late-stage Parkinson's disease

R Borgohain, N A. Mehta, O A. Bajenaru, R Quatrale, V Lucini, R Anand, for the Study 016 Investigators

2nd World Parkinson Conference (WPC) - Glasgow, Scotland, 28 September- 1 October 2010

 

Effect of safinamide on dyskinesia in patients with mid- to late-stage Parkinson's disease: data from a post-hoc analysis

M Bhatt, D Chirileanu, C Meshram, P Stanzione, E Forrest, V Lucini, for the Study 016 Investigators

2nd World Parkinson Conference (WPC) - Glasgow, Scotland, 28 September- 1 October 2010

 

Predicting exposure and response to safinamide in Parkinson's disease using population pharmacokinetic and pharmacodynamic modelling.

M Campioni, S Kroesser, M M. Thapar, S C. Hayes, E Gibiansky, V Lucini, R Anand

2nd World Parkinson Conference (WPC) - Glasgow, Scotland, 28 September- 1 October 2010

 

Effects of safinamide as add-on to L-dopa on symptom severity and aspects of daily living in patients with mid- to late-stage Parkinson's disease

J Szasz, R Borgohain, M Bhatt, S Rossetti, V Lucini, R Anand, for the Study 016 investigators

2nd World Parkinson Conference (WPC) - Glasgow, Scotland, 28 September- 1 October 2010

 

Safinamide improves motor function without worsening troublesome dyskinesia as add-on therapy in L-dopa-treated patients with mid- to late-stage Parkinson's disease

C Meshram, M Bhatt, D Chirileanu, P Stanzione, V Lucini, S Rossetti, R Anand, for the Study 016 Investigators

14th Congress of the European Federation of Neurological Societies (EFNS) - September 25-28, 2010 Geneva, Switzerland

 

Cognitive impairment in patients with mid- to late-stage Parkinson's disease

S De Santi, R Anand, V Lucini, P Rice for the Study 016 Investigators

14th Congress of the European Federation of Neurological Societies (EFNS) - September 25-28, 2010 - Geneva, Switzerland

 

Safinamide reduces levodopa-induced dyskinesia in MPTP-lesioned primates while prolonging anti-parkinsonian efficacy

L. Gregoire, A. Roach , T. Di Paolo

14th International Congress of Parkinson's Disease and Movement Disorders (MDS) /June 13-17, 2010, in Buenos Aires, Argentina

 

Cognitive deficits in patients with mid- to late-stage Parkinson's disease

Susan M De Santi, PhD, Ravi Anand, MD, Valentina Lucini, MD, Patricia Rice, PhD and the Study 016Investigators

14th International Congress of Parkinson's Disease and Movement Disorders (MDS) /June 13-17, 2010, in Buenos Aires, Argentina

 

SETTLE study design: a 24-week, double-blind, placebo-controlled study of the efficacy and safety of safinamide as add-on therapy to levodopa in patients with Parkinson's disease

Anthony H.V. Schapira, Susan Fox, Robert Hauser, Joseph Jankovic, Jaime Kulisevsky, Rajesh Pahwa,Werner Poewe, Florian von Raison, Christopher Kenney, Bruno Musch

14th International Congress of Parkinson's Disease and Movement Disorders (MDS) /June 13-17, 2010, in Buenos Aires, Argentina

 

Safinamide as add-on to levodopa improves motor function without worsening dyskinesia in patients with mid-late Parkinson's disease

Chandrashekhar M Meshram, MD, Mohit Bhatt, MD, Dana Chirileanu, MD, Paolo Stanzione, MD, Valentina
Lucini, MD, Stefano M Rossetti, MD, Ravi Anand, MD and the Study 016 Investigators

14th International Congress of Parkinson's Disease and Movement Disorders (MDS) /June 13-17, 2010, in Buenos Aires, Argentina

 

Effect of safinamide on depressive symptoms in patients with mid-late stage Parkinson's disease

Rupam Borgohain, MD, Neeta A Mehta, MD, Ovidiu A Bajenaru, MD, Rocco Quatrale, MD, Valentina Lucini,MD, Ravi Anand, MD and the Study 016 investigators

14th International Congress of Parkinson's Disease and Movement Disorders (MDS) /June 13-17, 2010, in Buenos Aires, Argentina

 

MOTION (safinaMide add-On To dopamine agonist in early Idiopathic ParkinsON's disease) study design: a 24-week, double-blind, placebo-controlled study of the efficacy and safety of safinamide

Paolo Barone, Hubert H. Fernandez, Joaquim J. Ferreira, Thomas Mueller, Marie Saint-Hilaire, Mark Stacy, Eduardo Tolosa, Florian von Raison, Christopher Kenney, Bruno Muschmide

14th International Congress of Parkinson's Disease and Movement Disorders (MDS) /June 13-17, 2010, in Buenos Aires, Argentina

 

Population Pharmacokinetics of Safinamide and its Effect on Disease Progression in Parkinson's Disease

M. Campioni , S. Kroesser, M.M. Thapar , S.C. Hayes, E. Gibiansky, V. Lucini R. Anand

PAGE (Population Approach Group Europe) conference, Berlin, 8-11 June 2010

 

Adjuvant activity of the novel sodium channel blocker NW-3509 in combination therapy with antipsychotics

Emanuela  Izzo, Alessandro Ieraci, Sara Meli, Marco Bortolato, Roberto Frau, Valentina Bini, Patricia  Salvati, Ravi Anand

XXVII Congress of the CINP (International College of Neuropsychopharmacology 6-10 June 2010 -Hong Kong

 

Ion channel blockers for the treatment of neuropathic pain                                           

Elena Colombo, Simona Francisconi, Laura Faravelli, Emanuela Izzo, Paolo Pevarello   

Future Medicinal Chemistry, May 2010, Vol. 2, No. 5, Pages 803-842

 

Effect of safinamide on levodopa-induced dyskinesia in patients with Parkinson's disease

M. Bhatt, D. Chirileanu, C. Meshram, P. Stanzione, E.  Forrest, V. Lucini for the Study 016 Investigators

62nd AAN Annual Meeting - April 10 -17, 2010 TORONTO, CANADA